Best Western South Carolina Hotels

Welcome to the Best Western Hotels of South Carolina. Here you'll find more than 25 SC hotel locations throughout the birthplace of southern hospitality. Choose from a great selection of Airport Hotels, Inn and Suites, Executive Inns, University Hotels, Downtown Hotels and more. We are located in great cities like Charleston, Columbia, Greenville, Myrtle Beach and more. Whether you're traveling for business, or seeking to take advantage of the many outdoor recreation opportunites across South Carolina, you'll find a comfortable Best Western hotel ready to serve you. Stay and save at Best Western, The World's Largest Hotel Chain® .

Find a Hotel

Choose a city in South Carolina Beaufort Bennettsville Charleston Columbia Conway Florence Fort Mill Greenville Ladson Latta Manning Mount Pleasant Myrtle Beach North Charleston North Myrtle Beach Orangeburg Piedmont Ridgeland Santee Seneca Spartanburg Sumter Walterboro

Make a Reservation

Select a Best Western in South Carolina Best Western Airport Inn & Suites, North Charleston Best Western Bennettsville Inn, Bennettsville Best Western Carowinds, Fort Mill Best Western Charleston Downtown Hotel, Charleston Best Western Executive Inn & Suites, Columbia Best Western Executive Inn Latta, Latta Best Western Executive Inn Seneca, Seneca Best Western Fort Jackson, Columbia Best Western Grand Strand Inn & Suites, Myrtle Beach Best Western Greenville Airport Inn, Greenville Best Western Guest Inn, Conway Best Western Inn Florence, Florence Best Western King Charles Inn, Charleston Best Western Magnolia Inn & Suites, Ladson Best Western Ocean Sands Beach Resort, North Myrtle Beach Best Western of Walterboro, Walterboro Best Western Orangeburg Inn & Suites, Orangeburg Best Western Palmetto Inn, Manning Best Western Patriots Point, Mount Pleasant Best Western Piedmont Inn & Suites, Piedmont Best Western Point South, Ridgeland Best Western Santee Inn, Santee Best Western Sea Island Inn, Beaufort Best Western Spartanburg Inn, Spartanburg Best Western Sumter Inn, Sumter Best Western Sweetgrass Inn, Charleston Best Western The Carolinian Beach Resort, Myrtle Beach

Rewards Program

4X the Rewards!

Earn double, triple or quadruple points when you stay 2, 3 or 4 nights! So, stay more & earn more with Best Western Rewards®.

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